Oxalic acid toxicity
Anticipatory
Can you differentiate
between tetanic convulsions and oxalic acid toxicity convulsions????
Objective
To be able to diagnose
oxalic acid toxicity rapidly.
Instructional content.
Chronic poisoning can occur from skin contact or inhalation with developing cyanosis and gangrene of the fingers.
Diagnostic symptom:
- agonizing pain, haematemesis of altered brown blood and shock within 10-15 minutes IF large dose is taken within short period of time.
Diagnostic sign
- Tremors and convulsions that involve the whole of the body muscles as oxalic acid unites with ionized calcium in the blood to form Ca oxalate resulting in hypocalcaemia.
- Anurea, with Ca oxalate , RBCs and proteins in urine
- Myocardial depression with low B.p.
Post mortem picture:
Superficial ulceration of gastric mucosa with adherent whitish powder of calcium oxalate.
- Kidney shows glomerulonphrities, swelling and engorgement of kidneys with clondy areas of Ca oxalate crystals.
- Dilated heart.
Diagnostic symptom:
- agonizing pain, haematemesis of altered brown blood and shock within 10-15 minutes IF large dose is taken within short period of time.
Diagnostic sign
- Tremors and convulsions that involve the whole of the body muscles as oxalic acid unites with ionized calcium in the blood to form Ca oxalate resulting in hypocalcaemia.
- Anurea, with Ca oxalate , RBCs and proteins in urine
- Myocardial depression with low B.p.
Post mortem picture:
Superficial ulceration of gastric mucosa with adherent whitish powder of calcium oxalate.
- Kidney shows glomerulonphrities, swelling and engorgement of kidneys with clondy areas of Ca oxalate crystals.
- Dilated heart.
Transition:
Metals Toxicity