Mercury.
Anticipatory
Do you know that mercury
Toxicity may develop as mass Toxicity involving large group of populations at
the same time?
Objective
- To learn how to diagnose mercurialism.
- To differentiate between acute and chronic cases.
- To differentiate between acute and chronic cases.
Instructional content.
- Most poisoning are due to methyl mercury as a result of eating contaminated fish and food polluted industrial wastes.
- Mercury has local irritant action on G.I.T and remote action as it combines with SH-tissue enzymes.
Clinical picture of acute poisoning:
Gastro - intestinal :
*Diarrhea with blood and mucus with dehydration within 24 hrs
Renal
*Rapidly progressive polyurea then oligurea ending with renal failure within 10 days.
Clinical picture of chronic poisoning: (Mercurialis)
Oral :
*Gingivitis with excessive salivation and grey line in the gums
Intestinal:
*Chronic diarrhea with mucus and blood (mercurial dysentery)
Nervous:
*Hatters shakes in the hands that increased during movement
Psychic:
*Mercurial erythism manifested by shyness, and vague fear.
Skin:
*Urticaria with strong itching till oozing of the serum.
Eye:
* Mercurialentis which is disolaration of the capsule of the eye
lens du to merury deposition (seen by slit-lamp)
Post mortem picture:
*Gastric mucosa discolored grey with hyperaemia and ulceration
*Grey discoloration of the caecum as it is the site of excretion of mercury.
*Evidence of chronic nephrities of the kidney
- Mercury has local irritant action on G.I.T and remote action as it combines with SH-tissue enzymes.
Clinical picture of acute poisoning:
Gastro - intestinal :
*Diarrhea with blood and mucus with dehydration within 24 hrs
Renal
*Rapidly progressive polyurea then oligurea ending with renal failure within 10 days.
Clinical picture of chronic poisoning: (Mercurialis)
Oral :
*Gingivitis with excessive salivation and grey line in the gums
Intestinal:
*Chronic diarrhea with mucus and blood (mercurial dysentery)
Nervous:
*Hatters shakes in the hands that increased during movement
Psychic:
*Mercurial erythism manifested by shyness, and vague fear.
Skin:
*Urticaria with strong itching till oozing of the serum.
Eye:
* Mercurialentis which is disolaration of the capsule of the eye
lens du to merury deposition (seen by slit-lamp)
Post mortem picture:
*Gastric mucosa discolored grey with hyperaemia and ulceration
*Grey discoloration of the caecum as it is the site of excretion of mercury.
*Evidence of chronic nephrities of the kidney
Multi-choiceHatters shacks are characteristic features of:
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Plumbism.
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Alcoholism.
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Mercuralism.
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Cocainism.
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Circle the statement that does not go along with the clinical picture of chronic mercury poisoning:
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The presence of grey line in gums.
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Tremors of the muscles of fingers
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Chronic constipation
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Psychic problems as an anxiety and vague fear.
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Transition:
Inhalants toxicity.